Prognosis of patients with liver cirrhosis: A multi?center retrospective observational study

Aim Despite advances in the management of liver diseases and changes etiology cirrhosis, few studies have updated prognosis cirrhosis. This study aimed to clarify recent cirrhosis identify risk factors for death. Methods In this retrospective observational by Hepatic Disease Network National Hospital Organization Japan, chart reviews were performed follow patients with beginning 2011. We conducted Kaplan–Meier survival time analyses stratified Child–Pugh classification albumin-bilirubin grade. Cox regression analysis was used Results identified 444 eligible from 25 hospitals, including 303 (68%), 110 (25%), 31 (7%) classes A, B, C, respectively. Hepatitis C virus infection cause 63% patients. The 1-year 5-year cumulative rates 90% 61%, 78% 42%, 65% 25%, grades 1, 2, 3 98% 80%, 91% 56%, 58% 23%, Cirrhosis (Child–Pugh albumin-bilirubin), age, cancer, untreated esophageal varices associated increased hazard Conclusions Little improvement observed compared previous reports, class remained poor. Untreated as a factor